最新发布
药学院
2017-07-10
11364
一、基本信息
孙世国,教授,博士研究生导师。绿洲学者,石河子大学特聘教授。等期刊编委,journal of the american chemical society(jacs)等20种国际学术期刊,以及部分国内学术期刊审稿人。发表论文160余篇,其中sci收录150余篇,入选综合化学类期刊2019 top 1% 高被引中国作者。先后主持nsfc-新疆联合基金重点项目1项,国家自然科学基金面上项目5项,省部级课题10余项。获授权中国发明专利37项(排名第一7项)、美国专利4项。参编英文书籍2部,获省部级科技奖励4项(一等奖1项,三等奖3项)。主要研究方向:功能材料及其光、电化学、影像学,包括荧光可视化检测材料在医药卫生、环境监测、食品安全等相关领域的应用;系统靶向药剂学(systematic targeting pharmaceutics, stp)包括组合药物、药物在体可视化成像追踪、药物靶向传递、精准定位、智能释放、安全给药等;光/电便携式可视化检测器件及材料开发。
二、学术经历
1. 2018-01~至今,石河子大学,药学院,绿洲学者特聘教授,博导
2. 2011-04至今,西北农林科技大学,化学与药学院,教授,博导
3. 2006-02~2016-03,大连理工大学,精细化工国家重点实验室,副教授,博导
三、教育经历
1. 2016-09~2007-03,美国阿克伦大学有机化学系客座访问
2. 2004-01~2005-12,瑞典皇家工学院,有机化学系,博士后
3. 2000-03~2003-08,大连理工大学,应用化学,博士
4. 1991-09~1994-01,苏州丝绸工学院(现更名苏州大学),染整专业,硕士
5. 1984-09~1988-07,河北轻化工学院(现更名河北科技大学),染整专业,学士
四、曾获奖励
印记和荧光复合检测系统在医药工业领域的应用,新疆生产建设兵团科技进步一等奖,李迎春,张波,孙世国,田丽萍,胡艳丽,王晓琴,唐辉,刘江,罗俊,赵飞浪,刘杰,宋晗,张路,黄彬铜,刘媛,2017年
五、主持科学研究项目
1. nsfc-新疆联合基金重点项目,u1803283,《宫颈癌多靶点精准控释给药及其作用机制研究》,起止年月:2019.01-2022.12,258万元,主持,在研
2. 国家自然科学基金面上项目,21878249,《hiv专一快速荧光可视化检测研究》,起止年月:2019.01-2022.12,66万元,主持,在研
3. 兵团重点领域科技攻关项目,2018ab012,《新疆甘草种植与药材质量提升关键技术研究》,起止年月:2018.01-2021.12,279万元,子课题负责人,在研
4. 自然科学基金面上项目,,《肿瘤淋巴转移监测用三重靶向近红外荧光造影研究》,起止年月:2015.01-2018.12,88万元,结题
5. 自然科学基金面上项目,21272030,《分子内与分子间协同作用型红绿光双发射ecl染料标记物研究》,起止年月:2013.01-2016.12,80万元,结题
六、讲授课程
硕士研究生:高级药理学、药学研究方法与论文写作
七、代表性成果
1. 代表论文
[1] zhenfu wen, fengyu liu*, guoxin liu, qinyan sun, yuhuan zhang, mehdi muhammad, yongqian xu, hongjuan li, shiguo sun*, assembly of multifunction dyes and heat shock protein 90 inhibitor coupled to bovine serum albumin in nanoparticles for multimodal photodynamic/photothermal/chemo-therapy, j. colloid interf. sci., 2021, 590, 290-300.
[2] zhenzhen xie, jia wen, shaowei sun, jing zhang, xiling deng, shichao han, lixia wang, bo zhang, chenglin hong*, shiguo sun*, in-vitro and in-vivo monitoring of gold(iii) ions from intermediate metabolite of sodium aurothiomalate through water-soluble ruthenium (ii) complex-based luminescent probe, bioorg. chem., 2021, 110, 104749.
[3] yasamin nasiri khonsari; shiguo sun*, a novel mip-ecl sensor based on rgo-ceo2np/ru(bpy)32 -chitosan for ultratrace determination of trimipramine, j. mater. chem. b, 2021, 9(2), 471-478.
[4] junna lu, fengyu liu, hongjuan li, yongqian xu, shiguo sun*, width-consistent mesoporous silica nanorods with a precisely controlled aspect ratio for lysosome dysfunctional synergistic chemotherapy/photothermal therapy/starvation therapy/oxidative therapy. acs appl. mater. inter., 2020, 12(22), 24611-24622.
[5] jing zhang, zihao yang, shanshan zhang, zhenzhen xie, shichao han, lixia wang, bo zhang*, shiguo sun*, investigation of endogenous malondialdehyde through fluorescent probe mda-6 during oxidative stress, anal. chim. acta, 2020, 1116, 9-15.
[6] zijian zhang, ting lv, binbin tao, zhenfu wen, yongqian xu, hongjuan li, fengyu liu*, shiguo sun*, a novel fluorescent probe based on naphthalimide for imaging nitroreductase (ntr) in bacteria and cells. bioorg. med. chem., 2020, 28(3), 115280.
[7] jia wen#, yinghua lv#, yongqian xu, pengfei zhang, hongjuan li, xiaoxu chen, xueliang li, lingkai zhang, fengyu liu*, wenxian zeng*, shiguo sun*, construction of a biodegradable, versatile nanocarrier for optional combination cancer therapy, acta biomater., 2019, 83, 359-371.
[8] tianjiao li#, qiwen chen#, yi zheng, pengfei zhang, xiaoxu chen, junna lu, yinghua lv, shiguo sun*, wenxian zeng*, pamam-crgd mediating efficient sirna delivery to spermatogonial stem cells, stem cell res. ther., 2019, 10, 399.
[9] yasamin nasiri khonsari, shiguo sun*, a novel label free electrochemiluminescent aptasensor for the detection of lysozyme, mater. sci. eng. c, 2019, 96, 146-152.
[10] zhenfu wen, fengyu liu*, qing chen, yongqian xu, hongjuan li, shiguo sun*, recent development on biodegradable nanovehicle delivery system-assisted immunotherapy, biomater. sci., 2019, 7, 4414-4443.
[11] junna lu, qiwen chen, xingcheng ding, jia wen, yuhuan zhang, hongjuan li, yongqian xu, fengyu liu*, su-shing chen*, shiguo sun*, bsa modified, disulfide-bridged mesoporous silica with low biotoxicity for dual-responsive drug delivery, micropor. mesopor. mat., 2019, 278, 256-266.
[12] jia wen, kui yang, xingcheng ding, hongjuan li, yongqian xu, fengyu liu*, shiguo sun*, in situ formation of homogeneous tellurium nanodots in paclitaxel-loaded mgal layered double hydroxide gated mesoporous silica nanoparticles for synergistic chemo/pdt/ptt trimode combinatorial therapy, inorg. chem., 2019, 58, 2987-2996.
[13] wan zhang, xiaoqian ji, kunlin chen, chaoxia wang*, shiguo sun*, thermochromic performance of a new temperature sensitive pigment based on rhodamine derivative in both liquid and solid systems, prog. org. coat., 2019, 137, 105280.
[14] fengyu liu*, jia wen, su-shing chen*, shiguo sun*, a luminescent bimetallic iridium(iii) complex for ratiometric tracking intracellular viscosity, chem. commun., 2018, 54, 1371-1374.
[15] ting lv, yongqian xu, hongjuan li, fengyu liu*, shiguo sun*, a rhodamine b-based fluorescent probe for imaging cu2 in maize roots, bioorgan. med. chem., 2018, 26, 1448-1452.
[16] jia wen#, yinghua lv#, pengyi xia#, fengyu liu*, yongqian xu, hongjuan li, su-shing chen*, shiguo sun*, a water-soluble near-infrared fluorescent probe for specific pd2 detection, bioorgan. med. chem., 2018, 26, 931-937.
[17] yasamin nasiri khonsari, shiguo sun*, electrochemiluminescent aptasensor for thrombin using nitrogen-doped graphene quantum dots, microchim. acta, 2018, 185, 430.
2. 发明专利
[1] 孙世国,慕道洲,彭孝军,蔡明珠,王继涛,光敏染料锇配合物及其制备方法、癌变早期dna氧化损伤快速检测试剂盒及其检测方法,中国发明专利,zl201310148539.7。
[2] 孙世国,王继涛,彭孝军,慕道洲,孙伟,一类双波长发射、双异核金属配合物、其制备方法及应用,中国发明专利,zl201310224080.4。
[3] 孙世国,彭孝军,李志勇,王继涛,八元瓜环自组装型分子信标及其制备方法和应用,中国发明专利,zl201310379653.0。
[4] 孙世国,孙立成,杨洋,彭孝军,樊江莉,刘凤玉。分子内带有吩噻嗪供电基团的三联吡啶钌/锇ecl标记物,中国发明专利,zl200910011139.5。
[5] 孙世国,孙立成,杨洋,彭孝军,樊江莉,刘凤玉。以不同长度碳链连接的双核三联吡啶钌/锇ecl标示物,中国发明专利,zl200910011299.x。
[6] 孙世国,刘凤玉,李福胜,染料与八元瓜环自组装化合物用于作为荧光探针的应用,中国发明专利,zl201110154078.5。
八、学术兼职
1. 美国化学会(american chemical society, acs)会员
2. 国家科技奖励评审专家
3. 教育部学位中心通讯评议专家
4. 科技部入库专家
5. 国家自然科学基金通讯评审人
6. 中国博士后基金评审专家
7. 高等学校博士学科点专项科研基金网络评审专家
九、2024正规欧洲杯平台的联系方式
1. e-mail:nwsuaf.edu.cn
2. 通讯地址:新疆维吾尔自治区石河子市,北2路59号,石河子大学医学校区,药学院
3. 邮编:832002
2017-07-10
药学院
11364
一、基本信息
孙世国,教授,博士研究生导师。绿洲学者,石河子大学特聘教授。等期刊编委,journal of the american chemical society(jacs)等20种国际学术期刊,以及部分国内学术期刊审稿人。发表论文160余篇,其中sci收录150余篇,入选综合化学类期刊2019 top 1% 高被引中国作者。先后主持nsfc-新疆联合基金重点项目1项,国家自然科学基金面上项目5项,省部级课题10余项。获授权中国发明专利37项(排名第一7项)、美国专利4项。参编英文书籍2部,获省部级科技奖励4项(一等奖1项,三等奖3项)。主要研究方向:功能材料及其光、电化学、影像学,包括荧光可视化检测材料在医药卫生、环境监测、食品安全等相关领域的应用;系统靶向药剂学(systematic targeting pharmaceutics, stp)包括组合药物、药物在体可视化成像追踪、药物靶向传递、精准定位、智能释放、安全给药等;光/电便携式可视化检测器件及材料开发。
二、学术经历
1. 2018-01~至今,石河子大学,药学院,绿洲学者特聘教授,博导
2. 2011-04至今,西北农林科技大学,化学与药学院,教授,博导
3. 2006-02~2016-03,大连理工大学,精细化工国家重点实验室,副教授,博导
三、教育经历
1. 2016-09~2007-03,美国阿克伦大学有机化学系客座访问
2. 2004-01~2005-12,瑞典皇家工学院,有机化学系,博士后
3. 2000-03~2003-08,大连理工大学,应用化学,博士
4. 1991-09~1994-01,苏州丝绸工学院(现更名苏州大学),染整专业,硕士
5. 1984-09~1988-07,河北轻化工学院(现更名河北科技大学),染整专业,学士
四、曾获奖励
印记和荧光复合检测系统在医药工业领域的应用,新疆生产建设兵团科技进步一等奖,李迎春,张波,孙世国,田丽萍,胡艳丽,王晓琴,唐辉,刘江,罗俊,赵飞浪,刘杰,宋晗,张路,黄彬铜,刘媛,2017年
五、主持科学研究项目
1. nsfc-新疆联合基金重点项目,u1803283,《宫颈癌多靶点精准控释给药及其作用机制研究》,起止年月:2019.01-2022.12,258万元,主持,在研
2. 国家自然科学基金面上项目,21878249,《hiv专一快速荧光可视化检测研究》,起止年月:2019.01-2022.12,66万元,主持,在研
3. 兵团重点领域科技攻关项目,2018ab012,《新疆甘草种植与药材质量提升关键技术研究》,起止年月:2018.01-2021.12,279万元,子课题负责人,在研
4. 自然科学基金面上项目,,《肿瘤淋巴转移监测用三重靶向近红外荧光造影研究》,起止年月:2015.01-2018.12,88万元,结题
5. 自然科学基金面上项目,21272030,《分子内与分子间协同作用型红绿光双发射ecl染料标记物研究》,起止年月:2013.01-2016.12,80万元,结题
六、讲授课程
硕士研究生:高级药理学、药学研究方法与论文写作
七、代表性成果
1. 代表论文
[1] zhenfu wen, fengyu liu*, guoxin liu, qinyan sun, yuhuan zhang, mehdi muhammad, yongqian xu, hongjuan li, shiguo sun*, assembly of multifunction dyes and heat shock protein 90 inhibitor coupled to bovine serum albumin in nanoparticles for multimodal photodynamic/photothermal/chemo-therapy, j. colloid interf. sci., 2021, 590, 290-300.
[2] zhenzhen xie, jia wen, shaowei sun, jing zhang, xiling deng, shichao han, lixia wang, bo zhang, chenglin hong*, shiguo sun*, in-vitro and in-vivo monitoring of gold(iii) ions from intermediate metabolite of sodium aurothiomalate through water-soluble ruthenium (ii) complex-based luminescent probe, bioorg. chem., 2021, 110, 104749.
[3] yasamin nasiri khonsari; shiguo sun*, a novel mip-ecl sensor based on rgo-ceo2np/ru(bpy)32 -chitosan for ultratrace determination of trimipramine, j. mater. chem. b, 2021, 9(2), 471-478.
[4] junna lu, fengyu liu, hongjuan li, yongqian xu, shiguo sun*, width-consistent mesoporous silica nanorods with a precisely controlled aspect ratio for lysosome dysfunctional synergistic chemotherapy/photothermal therapy/starvation therapy/oxidative therapy. acs appl. mater. inter., 2020, 12(22), 24611-24622.
[5] jing zhang, zihao yang, shanshan zhang, zhenzhen xie, shichao han, lixia wang, bo zhang*, shiguo sun*, investigation of endogenous malondialdehyde through fluorescent probe mda-6 during oxidative stress, anal. chim. acta, 2020, 1116, 9-15.
[6] zijian zhang, ting lv, binbin tao, zhenfu wen, yongqian xu, hongjuan li, fengyu liu*, shiguo sun*, a novel fluorescent probe based on naphthalimide for imaging nitroreductase (ntr) in bacteria and cells. bioorg. med. chem., 2020, 28(3), 115280.
[7] jia wen#, yinghua lv#, yongqian xu, pengfei zhang, hongjuan li, xiaoxu chen, xueliang li, lingkai zhang, fengyu liu*, wenxian zeng*, shiguo sun*, construction of a biodegradable, versatile nanocarrier for optional combination cancer therapy, acta biomater., 2019, 83, 359-371.
[8] tianjiao li#, qiwen chen#, yi zheng, pengfei zhang, xiaoxu chen, junna lu, yinghua lv, shiguo sun*, wenxian zeng*, pamam-crgd mediating efficient sirna delivery to spermatogonial stem cells, stem cell res. ther., 2019, 10, 399.
[9] yasamin nasiri khonsari, shiguo sun*, a novel label free electrochemiluminescent aptasensor for the detection of lysozyme, mater. sci. eng. c, 2019, 96, 146-152.
[10] zhenfu wen, fengyu liu*, qing chen, yongqian xu, hongjuan li, shiguo sun*, recent development on biodegradable nanovehicle delivery system-assisted immunotherapy, biomater. sci., 2019, 7, 4414-4443.
[11] junna lu, qiwen chen, xingcheng ding, jia wen, yuhuan zhang, hongjuan li, yongqian xu, fengyu liu*, su-shing chen*, shiguo sun*, bsa modified, disulfide-bridged mesoporous silica with low biotoxicity for dual-responsive drug delivery, micropor. mesopor. mat., 2019, 278, 256-266.
[12] jia wen, kui yang, xingcheng ding, hongjuan li, yongqian xu, fengyu liu*, shiguo sun*, in situ formation of homogeneous tellurium nanodots in paclitaxel-loaded mgal layered double hydroxide gated mesoporous silica nanoparticles for synergistic chemo/pdt/ptt trimode combinatorial therapy, inorg. chem., 2019, 58, 2987-2996.
[13] wan zhang, xiaoqian ji, kunlin chen, chaoxia wang*, shiguo sun*, thermochromic performance of a new temperature sensitive pigment based on rhodamine derivative in both liquid and solid systems, prog. org. coat., 2019, 137, 105280.
[14] fengyu liu*, jia wen, su-shing chen*, shiguo sun*, a luminescent bimetallic iridium(iii) complex for ratiometric tracking intracellular viscosity, chem. commun., 2018, 54, 1371-1374.
[15] ting lv, yongqian xu, hongjuan li, fengyu liu*, shiguo sun*, a rhodamine b-based fluorescent probe for imaging cu2 in maize roots, bioorgan. med. chem., 2018, 26, 1448-1452.
[16] jia wen#, yinghua lv#, pengyi xia#, fengyu liu*, yongqian xu, hongjuan li, su-shing chen*, shiguo sun*, a water-soluble near-infrared fluorescent probe for specific pd2 detection, bioorgan. med. chem., 2018, 26, 931-937.
[17] yasamin nasiri khonsari, shiguo sun*, electrochemiluminescent aptasensor for thrombin using nitrogen-doped graphene quantum dots, microchim. acta, 2018, 185, 430.
2. 发明专利
[1] 孙世国,慕道洲,彭孝军,蔡明珠,王继涛,光敏染料锇配合物及其制备方法、癌变早期dna氧化损伤快速检测试剂盒及其检测方法,中国发明专利,zl201310148539.7。
[2] 孙世国,王继涛,彭孝军,慕道洲,孙伟,一类双波长发射、双异核金属配合物、其制备方法及应用,中国发明专利,zl201310224080.4。
[3] 孙世国,彭孝军,李志勇,王继涛,八元瓜环自组装型分子信标及其制备方法和应用,中国发明专利,zl201310379653.0。
[4] 孙世国,孙立成,杨洋,彭孝军,樊江莉,刘凤玉。分子内带有吩噻嗪供电基团的三联吡啶钌/锇ecl标记物,中国发明专利,zl200910011139.5。
[5] 孙世国,孙立成,杨洋,彭孝军,樊江莉,刘凤玉。以不同长度碳链连接的双核三联吡啶钌/锇ecl标示物,中国发明专利,zl200910011299.x。
[6] 孙世国,刘凤玉,李福胜,染料与八元瓜环自组装化合物用于作为荧光探针的应用,中国发明专利,zl201110154078.5。
八、学术兼职
1. 美国化学会(american chemical society, acs)会员
2. 国家科技奖励评审专家
3. 教育部学位中心通讯评议专家
4. 科技部入库专家
5. 国家自然科学基金通讯评审人
6. 中国博士后基金评审专家
7. 高等学校博士学科点专项科研基金网络评审专家
九、2024正规欧洲杯平台的联系方式
1. e-mail:nwsuaf.edu.cn
2. 通讯地址:新疆维吾尔自治区石河子市,北2路59号,石河子大学医学校区,药学院
3. 邮编:832002